James Cook Week 8 Preview vs. the Panthers

James Cook will be up against the eighth-best run defense in the league when his Buffalo Bills meet the Carolina Panthers in Week 8, on Sunday at 1 p.m. ET.

This year, Cook has collected a team-leading 537 yards on 107 attempts (89.5 ypg), with five rushing TDs. In the passing game, Cook has grabbed 12 balls for 89 yards (14.8 ypg) this year.

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Cook vs. the Panthers

• Cook vs the Panthers (since 2021): No games
• One opposing rusher has recorded 100 or more rushing yards in a matchup against the Panthers during the 2025 season.
• Carolina has allowed five opposing rushers to record one or more TDs on the groun against them this year.
• The Panthers have not allowed any opposing players to record two or more rushing TDs against them this season.
• The rush defense of the Panthers is conceding 92.6 yards per outing on the ground this year, which ranks eighth in the NFL.
• Opponents of the Panthers have put up five touchdowns on the ground (0.7 per game). The Panthers' defense is 13th in the NFL in that category.

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Cook Rushing Insights

• Cook has hit the over on his rushing yards totals in four games (66.7%) out of six opportunities.
• The Bills, who are 12th in NFL play in points scored, have passed 49.2% of the time while running 50.8%.
• He has carried the ball in 107 of his team's 186 total rushing attempts this season (57.5%).
• Cook has at least one trip to the end zone as a runner in four games this year, with multiple rushing TDs once.
• He has five total touchdowns this season (25.0% of his team's 20 offensive TDs).
• He has 20 red zone carries for 55.6% of the team share (his team runs on 54.5% of its plays in the red zone).

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Cook's Recent Performance