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The Iowa State Cyclones (6-0) aim to continue a six-game win streak when they host the Syracuse Orange (4-2) on November 26, 2025 at MGM Grand Garden Arena.
Wednesday's game between the Cyclones and the Orange sees the Cyclones as a strong, 9.5-point favorite. The over/under is 152.5 points for the game.
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Iowa State vs. Syracuse Odds and Game Info
- Game day: Wednesday, November 26, 2025
- Game time: 1 p.m. ET
- TV channel: TNT
- Location: Las Vegas, Nevada
- Arena: MGM Grand Garden Arena
- Live stream: Watch this match on HBO Max (Regional restrictions may apply)
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Iowa State vs. Syracuse Odds and Prediction
- Spread favorite: Iowa State (-9.5)
- Moneyline: Iowa State (-588), Syracuse (+430)
- Total: 152.5 points
Pick ATS:Syracuse (+9.5)
- Pick OU: Under (152.5)
- Prediction: Iowa State 78, Syracuse 69
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Iowa State vs. Syracuse Comparison
| Iowa State Rank | Iowa State Stat | Syracuse Stat | Syracuse Rank | |
|---|---|---|---|---|
| 35th | 90.5 | Points Scored | 76.7 | 211th |
| 45th | 65.2 | Points Allowed | 60.3 | 8th |
| 67th | 17.2 | Assists | 15.3 | 150th |
| 31st | 9.2 | Turnovers | 8.5 | 13th |
| 19th | 51.7% | Field Goal % | 47.2% | 117th |
| 119th | 41.6% | Field Goal % Allowed | 34.1% | 3rd |
Iowa State Key Players
- The Cyclones leader in points and assists is Tamin Lipsey, who puts up 18.4 points per game to go with 5.2 assists.
- Joshua Jefferson leads Iowa State in rebounding, pulling down 8.2 boards per game while also scoring 18.3 points a contest.
- Milan Momcilovic leads the Cyclones in three-point shooting, making an average of 3.3 shots per game from beyond the arc.
- Lipsey is Iowa State's leader in steals, averaging 3.2 steals per game, while Blake Buchanan leads them in blocks with 1.5 per contest.
Syracuse Key Players
- Kiyan Anthony is at the top of the Orange scoring leaderboard with 12.5 points per game. Anthony also pulls down 2.7 rebounds and averages 1.3 assists per game.
- Syracuse's leader in rebounds is William Kyle III with 9.0 per game, and its leader in assists is Naithan George with 5.5 per game.
- Tyler Betsey is consistent from three-point range and leads the Orange with 2.4 made threes per game.
- Syracuse's leader in steals is George (1.7 per game), and its leader in blocks is Kyle (2.5 per game).
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